Progeria

Also known as Hutchinson-Gilford or HGPS. Caused by mutation in gene Lamin A found on chromosome 1. 

Hutchinson-Gilford Progeria Syndrome (Progeria) is a rare, fatal genetic condition characterized by an appearance of accelerated aging in children. Although they are born looking healthy, children with Progeria begin to display many characteristics of accelerated aging at around 18-24 months of age. Progeria signs include growth failure, loss of body fat and hair, aged-looking skin, stiffness of joints, hip dislocation, generalized atherosclerosis, cardiovascular (heart) disease and stroke.